Effects of Socio-demographic Factors on Regimen Adherence among Tuberculosis Patients in Kisumu Region, Kenya

Morris Senghor Shisanya

Abstract


Introduction

Efforts to diagnose TB and patients on treatment have been very successful as per WHO targets for Kenya. However, there are still poor treatment outcomes in a significant number of the patients. These poor treatment outcomes have been significantly linked to poor adherence to TB treatment.

Methods

This was a cross sectional descriptive study that was conducted in Kisumu East District to establish the effects of socio-demographic factors on regimen adherence among tuberculosis patients aged above 18 years attending TB clinics in Kisumu region, in Western Kenya. The data was analyzed using descriptive statistics and bivariate analysis and binary logistic regression. P values, Adjusted Odds Ratios with 95% confidence interval (CI) were used to demonstrate significance and strength of association between the socio-demographic factors and adherence. Significance was assumed at P value ≤0.05.

Findings

Residence; (OR:21.8; 95% CI:5.4-87.5 ;P<0.001), number of family members(OR:5.7; 95% CI:1.7-19.1 ;P=0.005) and sex of the patient  (OR:0.2; 95% CI: 0.0-0.9 ;P<0.036) were the significant socio-demographic aspects that predicted adherence.

Conclusion

Therefore some socio-demographic aspects of TB patients key predictors of adherence. These aspects can serve as a guide for flagging some patient as having potential for non-adherence thus appropriate follow-up measures instituted in time. It is important to establish the effects of socio-demographic aspects on adherence in every TB care setting for appropriate follow-up.


Keywords


Tuberculosis, adherence, socio-demographic

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References


Amuha, M. G., Kutyabami, P., Kitutu, F. E., Odoi-Adome, R., & Kalyango, J. N. (2009). Non-adherence to anti-TB drugs among TB/HIV co-infected patients in Mbarara Hospital Uganda: prevalence and associated factors. African Health Sciences, 9 Suppl 1(Suppl 1), S8-15. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/20589161

Anyaike, C., Musa, O. I., Babatunde, O. A., Bolarinya, O. A., Durowade, K. A., & Ajayi, O. S. (2013). ADHERENCE TO TUBERCULOSIS THERAPY IN UNILORIN TEACHING HOSPITAL, ILORIN, NORTH-CENTRAL NIGERIA. International Journal of Science Technology, 2(6), 2278–3687. Retrieved from http://www.ijset.net/journal/222.pdf

Balbay, O., Annakkaya, A. N., Arbak, P., Bilgin, C., & Erbas, M. (2005). Which Patients Are Able To Adhere to Tuberculosis Treatment? A Study in a Rural Area in the Northwest Part of Turkey. Japanese Journal of Infectious Diseases, 58, 152–158.

Belén, M., & Alende, O. (2012). Predictive factors of non-adherence to tuberculosis treatment in the metropolitan area of Buenos Aires, Argentina Factores predictivos de la no adherencia al tratamiento de la tuberculosis en municipios del Área Metropolitana de Buenos Aires, Argentina, 8, 65–76

Berhe, G., Enquselassie, F., & Aseffa, A. (2012). Treatment outcome of smear-positive pulmonary tuberculosis patients in Tigray Region, Northern Ethiopia. BMC Public Health, 12(1), 537. http://doi.org/10.1186/1471-2458-12-537

Caylà, J. A., Rodrigo, T., Ruiz-Manzano, J., Caminero, J. A., Vidal, R., García, J. M., … Sánchez, F. (2009). Tuberculosis treatment adherence and fatality in Spain. Respiratory Research, 10(1), 121. http://doi.org/10.1186/1465-9921-10-121

Cherkaoui, I., Sabouni, R., Ghali, I., Kizub, D., Billioux, A. C., Bennani, K., … Dooley, K. E. (2014). Treatment Default amongst Patients with Tuberculosis in Urban Morocco: Predicting and Explaining Default and Post-Default Sputum Smear and Drug Susceptibility Results. PLoS One, 9, e93574. http://doi.org/10.1371/journal.pone.0093574

DLTLD. (2010). Tuberculosis in Kenya. Division of Leprosy, Tuberculosis and Lung Diseases. Retrieved from http://www.nltp.co.ke/tbkenya.html

Dworkin, M. S., Adams, M. R., Cohn, D. L., Davidson, A. J., Buskin, S., Horwitch, C., … Jones, J. L. (2005). Factors that complicate the treatment of tuberculosis in HIV-infected patients. Journal of Acquired Immune Deficiency Syndromes, 39(4), 464–470. http://doi.org/10.1097/01.qai.0000152400.36723.85

Eticha, T., & Kassa, E. (2014). Bioanalysis & Biomedicine. J Bioanalysis and Biomedicine, 6, 61–646. http://doi.org/10.4172/1948-593X.1000113

Hirsch-Moverman, Y., Daftary, A., Franks, J., & Colson, P. W. (2008). Adherence to treatment for latent tuberculosis infection: systematic review of studies in the US and Canada. Int J Tuberc Lung Dis, 12(11), 1235–1254. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18926033

Kendall, E. A., Theron, D., Franke, M. F., van Helden, P., Victor, T. C., Murray, M. B., … Jacobson, K. R. (2013). Alcohol, hospital discharge, and socioeconomic risk factors for default from multidrug resistant tuberculosis treatment in rural South Africa: a retrospective cohort study. PLoS One, 8(12), e83480. http://doi.org/10.1371/journal.pone.0083480PONE-D-13-37002 [pii]

Nackers, F., Huerga, H., Espié, E., Aloo, A. O., Bastard, M., Etard, J.-F., … Bonnet, M. (2012). Adherence to Self-Administered Tuberculosis Treatment in a High HIV-Prevalence Setting: A Cross-Sectional Survey in Homa Bay, Kenya. PLoS ONE, 7(3), e32140. http://doi.org/10.1371/journal.pone.0032140

Naidoo, P., Peltzer, K., Louw, J., Matseke, G., McHunu, G., & Tutshana, B. (2013). Predictors of tuberculosis (TB) and antiretroviral (ARV) medication non-adherence in public primary care patients in South Africa: a cross sectional study. BMC Public Health, 13, 396. http://doi.org/1471-2458-13-396 [pii]10.1186/1471-2458-13-396

Okanurak, K., Kitayaporn, D., & Akarasewi, P. (2008). Factors contributing to treatment success among tuberculosis patients: a prospective cohort study in Bangkok. The International Journal of Tuberculosis and Lung Disease : The Official Journal of the International Union against Tuberculosis and Lung Disease, 12(10), 1160–5. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/18812046

Peltzer, K., & Pengpid, S. (2013). Socioeconomic factors in adherence to HIV therapy in low- and middle-income countries. J Health Popul Nutr, 31(2), 150–170. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=23930333

Peltzer, K., & Pengpid, S. (2015). Predictors of Non-adherence to Anti-Tuberculosis Medication in Tuberculosis Patients in Thailand. J Hum Ecol, 52(12), 26–31.

Sendagire, I., Schim Van der Loeff, M., Kambugu, A., Konde-Lule, J., & Cobelens, F. (2012). Urban Movement and Alcohol Intake Strongly Predict Defaulting from Tuberculosis Treatment: An Operational Study. PLoS ONE, 7(5), e35908. http://doi.org/10.1371/journal.pone.0035908

Suwankeeree, W., & Picheansathian, W. (2014). Strategies to promote adherence to treatment by pulmonary tuberculosis patients: a systematic review. Int J Evid Based Healthc, 12(1), 3–16. http://doi.org/10.1097/01.XEB.0000444614.17658.4601787381-201403000-00002 [pii]

Tesfahuneygn, G., Medhin, G., Legesse, M., Volmink, J., Garner, P., Dooley, K., … Lindtjørn, B. (2015). Adherence to Anti-tuberculosis treatment and treatment outcomes among tuberculosis patients in Alamata District, northeast Ethiopia. BMC Research Notes, 8(1), 503. http://doi.org/10.1186/s13104-015-1452-x

Xu, W., Lu, W., Zhou, Y., Zhu, L., Shen, H., & Wang, J. (2009). Adherence to anti-tuberculosis treatment among pulmonary tuberculosis patients: a qualitative and quantitative study. BMC Health Services Research, 9(1), 169. http://doi.org/10.1186/1472-6963-9-169

Zhou, C., Chu, J., Liu, J., Gai Tobe, R., Gen, H., Wang, X., … Xu, L. (2013). Adherence to tuberculosis treatment among migrant pulmonary tuberculosis patients in Shandong, China: a quantitative survey study. PLoS One, 7(12), e52334. http://doi.org/10.1371/journal.pone.0052334PONE-D-12-23709 [pii]


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